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January 2022
Quarterly updates from the National Institutes of Health (NIH) Office of Disease Prevention (ODP) including upcoming events, funding opportunities, and resources to help you conduct high-quality prevention research.
We want this information to be valuable to you, so please send your feedback and suggestions to prevention@nih.gov.
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I am excited to share our Spotlight on 2021 annual report, highlighting some of the ODP’s accomplishments this past year. In addition to the progress made on the key projects featured in the report, which I hope you will take the time to explore, 2021 was a special year for the ODP because it marked the 35th anniversary of our Office. I would like to recognize all the work that has been done to increase the scope, quality, dissemination, and impact of prevention research at the NIH since our Office’s founding in 1986.
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New Year, New Resource: Stepped Wedge Group-Randomized Trials
The NIH Research Methods Resources (RMR) website, which is managed by the ODP, now includes information about stepped wedge group-randomized trials (SWGRTs). SWGRTs are group-randomized trials (GRTs) that allow each group to cross from control to intervention at a prespecified time and in a random, staggered order. These trials have become quite common over the last 15 years, particularly in the evaluation of health care delivery interventions. On the RMR site, you will find background material and references on how to use SWGRTs, as well as a new sample size calculator that accommodates the three most-used versions of SWGRTs.
In addition to SWGRTs, the RMR website features materials and sample size calculators for parallel GRTs and individually randomized group-treatment (IRGT) trials. NIH funding opportunities that may involve trials that randomize and/or deliver interventions to groups now often encourage investigators to use the information, references, and three custom-built sample size calculators on the RMR site in their research applications. Investigators proposing these types of trials need to satisfy the NIH's clinical research requirements and show that the selected methodology, statistical analysis, and sample size are appropriate.
We hope you will refer to the RMR site often and help us spread the word about these resources. Please email rmr@od.nih.gov with any questions or feedback.
Seeking Volunteers To Help Enhance the ODP Website
Help us improve prevention.nih.gov! The ODP is looking for volunteers from the prevention research community to participate in a 20-to 30-minute Zoom interview with an outside research group. Your feedback will help us better understand:
- The usability of the ODP website
- The types of information and resources you need and rely upon
- The ease or difficulty of finding or accessing information and resources you need
We appreciate your insights! Your comments will be aggregated with other participant comments, and your name will not be used in any report or summary that may be shared with the ODP.
Still Time To Comment on the Workshop Panel's Draft Report!
An unbiased, independent panel developed a draft report following the recent NIH Pathways to Prevention Workshop: Improving Rural Health Through Telehealth-Guided Provider-to-Provider Communication. The draft report summarizes workshop discussions and identifies future research priorities. Comments will be accepted through February 4, 2022.
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Prevention Research Funding Opportunities
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Featuring upcoming funding opportunities in vaccine hesitancy, electronic nicotine delivery systems, and tobacco use. Find more than 300 other funding opportunities on our website related to topics and research methods in the field of prevention.
Notice of Special Interest (NOSI): Research to Address Vaccine Hesitancy, Uptake, and Implementation among Populations that Experience Health Disparities [NOT-MD-22-006]
First available due date: February 5, 2022
Two NOSIs on electronic nicotine delivery systems and alternative nicotine and tobacco delivery systems (NOT-OD-21-127 and NOT-OD-21-137) have been replaced. The reissued NOSIs, listed below, were published in the NIH Guide on December 9, 2021, along with two Notices of Early Expiration (NOT-OD-22-024 and NOT-OD-22-025).
First available due date: February 5, 2022
Center for Rapid Surveillance of Tobacco (CRST) to Assess Changes in Use Behaviors, Product Marketing, and the Marketplace (U01 Clinical Trial Not Allowed) [RFA-OD-22-002]
Next application date: May 18, 2022
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Dr. Xin Zhou from Yale School of Public Health introduced and demonstrated two new methods for power calculations to improve stepped wedge designs in this recent Mind the Gap webinar.
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2021 ODP Co-Funded Prevention Research
The ODP provides limited co-funding to support NIH Institutes, Centers and Offices, and other federal partners in prevention, particularly for initiatives to address gaps in research and practice. Check out the more than 50 disease prevention grants, workshops, and federal initiatives the ODP helped fund in 2021!
New Publications on Evidence Gaps Related to Physical Activity for Wheelchair Users
Three new reports from the NIH Pathways to Prevention Workshop: Can Physical Activity Improve the Health of Wheelchair Users? are now available:
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Upcoming Staff Presentations
Has Tobacco Regulatory Science Expanded Interest in Tobacco Research?
Poster presented by Helen I. Meissner, Ph.D., Sc.M., at the Society for Research on Nicotine and Tobacco Annual Meeting, March 16, 2022, at 1:00 p.m. ET
Staff Publications
Influential methods reports for group-randomized trials and related designs
Murray DM. Clinical Trials. 2022 Jan 6:17407745211063423. doi: 10.1177/17407745211063423. Epub ahead of print. PMID: 34991379.
NIH Tobacco Research and the Emergence of Tobacco Regulatory Science
Meissner HI, Sharma K, Mandal RJ, Cazarin MG, Wanke KL, Moyer J, Liggins C. Nicotine & Tobacco Research. 2021 Oct 8:ntab205. doi: 10.1093/ntr/ntab205. Epub ahead of print. PMID: 34624889.
Staff Achievements
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The ODP's resident statistician, Jon Moyer, was awarded his Ph.D. in biostatistics from the University of Massachusetts Amherst in December 2021. Congratulations, Dr. Moyer!
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Congratulations to the ODP's Wanda Hill on her 40+ years of Federal Service! Thank you, Wanda, for all you do to keep the ODP running smoothly no matter what the day has in store!
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New Staff
Bobby Gibson
Management Analyst
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