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July 2021
Quarterly updates from the National Institutes of Health (NIH) Office of Disease Prevention (ODP) including upcoming events, funding opportunities, and resources to help you conduct high-quality prevention research.
We want this information to be valuable to you, so please send your feedback and suggestions to prevention@nih.gov.
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New and Updated Resources Available To Help Design Rigorous Clinical Trials
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The NIH embarked on a series of initiatives in recent years to enhance the quality, efficiency, accountability, and transparency of our supported clinical research. While we are all making great progress, there are still concerns about clinical trials that are overly complex, have small sample sizes, or rely on surrogate end points that lack clinical relevance.
In 2017, we launched the NIH Research Methods Resources (RMR) website to help address these concerns. Since the site was recently revamped, we wanted to spotlight the new available tools and resources that can help you better plan the design, conduct, and analysis of rigorous NIH-defined clinical trials.
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Did you know? ODP Director Dr. David Murray leads a free, self-paced, seven-part online course to help researchers design and analyze pragmatic and group-randomized trials in public health and medicine. It includes video presentations, slide sets, suggested reading materials, and guided activities.
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Upcoming Pathways to Prevention Workshop on Provider-to-Provider Telehealth in Rural Areas
The NIH is hosting the Pathways to Prevention Workshop: Improving Rural Health Through Telehealth-Guided Provider-to-Provider Communication on October 12–14, 2021. This virtual workshop is free and open to the public.
About one-fifth of all people in the United States live in rural areas, which have higher mortality rates, a higher prevalence of diseases, and lower life expectancy than urban areas. Health care providers may be able to use telehealth to collaborate and improve rural health outcomes, but more research is needed.
Workshop speakers will identify those research gaps and explore barriers to and facilitators of successful and sustainable implementation of provider-to-provider telehealth in rural settings. Attendees will have opportunities to submit questions and comments during discussion periods. After weighing the evidence, an independent panel will prepare a report that summarizes the workshop and outlines future research priorities.
The workshop is co-sponsored by the ODP; National Center for Advancing Translational Sciences; National Heart, Lung, and Blood Institute; Health Resources & Services Administration; and Centers for Disease Control and Prevention.
New Analysis of the NIH Prevention Research Portfolio
Our most recent analysis of the NIH portfolio shows new awards classified as prevention research increased to 20.7% in 2019, and fiscal year 2019 marked the third consecutive annual increase in the percentage of projects and dollars used for new prevention research. However, the findings suggest more research is needed to test new interventions and disseminate existing interventions to address the leading risk factors for death, particularly in populations that experience health disparities.
Additional results include:
- A large proportion of prevention research projects included observational studies (63.9%), analysis of existing data (46.5%), or methods research (24.0%).
- Projects using a randomized clinical trial design represented just over a tenth (12.3%) of the NIH prevention research portfolio.
The ODP’s portfolio analysis work helps identify patterns and trends in disease prevention research and areas that may benefit from targeted efforts by the NIH. The ODP has also developed better approaches to describe NIH-funded prevention research and summarize study findings in a meaningful way.
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Prevention Research Funding Opportunities
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Measures Registry: Resources for Measuring Diet and Physical Activity
National Collaborative on Childhood Obesity Research
Searchable database of common measures and research methods for childhood obesity research at the individual, community, and population levels.
National Institute of Mental Health Data Archive (NDA)
National Institute of Mental Health
Human subjects data collected from hundreds of research projects across many scientific domains. NDA provides infrastructure for sharing research data, tools, methods, and analyses enabling collaborative science and discovery. De-identified human subjects data, harmonized to a common standard, are available to qualified researchers. Summary data are available to all.
Sun Safety Evidence-Based Programs
National Cancer Institute
Searchable database of evidence-based sun safety programs designed to provide program planners and public health practitioners easy and immediate access to program materials.
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Multilevel Physical Activity Interventions Notice of Special Interest—Technical Assistance Webinar
This pre-application webinar—recorded June 8, 2021—provides an overview of the new Notice of Special Interest (NOSI): Developing and Testing Multilevel Physical Activity Interventions to Improve Health and Well-Being (NOT-OD-21-087) and addresses questions from prospective applicants. The webinar recording and slides, as well as a list of frequently asked questions, are available online. The NOSI is active until February 2024.
Methods: Mind the Gap Webinar—Design and Analytic Methods for Group-Based Interventions
NIH Associate Director for Prevention and ODP Director Dr. David Murray reviews the design and analytic challenges of group-based interventions and demonstrates a new sample size calculator for individually randomized group-treatment trials in this Methods: Mind the Gap webinar recorded June 29, 2021.
2021 Early-Stage Investigator Lectures
The ODP’s annual Early-Stage Investigator Lecture recognizes prevention scientists who are poised to become future leaders in prevention research. Watch our 2021 winners’ lectures today.
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Staff Publications
Introduction to the Methods for Assessing the Impact of Screening in Childhood on Health Outcomes Supplement
Bianchi DW, Murray DM. Pediatrics. 2021 Jul;148(Suppl 1):s1–s2. doi: 10.1542/peds.2021-050693B. PMID: 34210840.
Challenges and Opportunities to Bolster the Effectiveness of Childhood Screening
King RB, Neilson E, King TM. Pediatrics. 2021 Jul;148(Suppl 1):s51–s55. doi: 10.1542/peds.2021-050693K. PMID: 34210849.
Measuring Multimorbidity: Selecting the Right Instrument for the Purpose and the Data Source
Suls J, Bayliss EA, Berry J, Bierman AS, Chrischilles EA, Farhat T, Fortin M, Koroukian SM, Quinones A, Silber JH, Ward BW, Wei M, Young-Hyman D, Klabunde CN. Medical Care. 2021 May 11. doi: 10.1097/MLR.0000000000001566. Epub ahead of print. PMID: 33974576.
National Institutes of Health Advancing Multimorbidity Research
Salive ME, Suls J, Farhat T, Klabunde CN. Medical Care. 2021 Jul 1;59(7):622–624. doi: 10.1097/MLR.0000000000001565. Epub ahead of print. PMID: 33900269.
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